• AHA
  • ESC
  • ASCO
  • ACC
  • RSNA
  • ISC
  • SABCS
  • AACR
  • APA
  • Archives
株式会社ヘスコインターナショナルは、法令を遵守し本サイトをご利用いただく皆様の個人情報の取り扱いに細心の注意を払っております。

Participants in clinical trials do not have a significant difference in outcome compared with patients not in trials

Data from more than two dozen published cancer studies comparing outcomes among trial participants and patients not in clinical trials suggest trial participants do not have better outcomes, according to an article in the January 24th issue of Lancet.

"Clinical trials are critical to the advancement of cancer care, but it is important that people who enroll in a study understand that their participation is intended primarily to benefit future patients," said Jeffrey M. Peppercorn, MD, MPH, lead author.

In the current work, American researchers reviewed 26 published studies that compared the outcomes of cancer patients enrolled in a clinical trial with patients who were not enrolled in the trial. Of the 26 studies, 14 showed some evidence that trial participants had better outcomes; however, only 9 of the trials were designed to compare the outcomes of the participants with non-participants who would have been eligible for the trials. Of those 9 studies, 3 suggested better outcomes among trial participants than among non-participants. No studies showed that participants had worse outcomes than non-participants.

"We found a few instances in which cancer trial participants may have had better outcomes than non-participants, but the limitations of the data we reviewed made it difficult to establish a definitive link between trial participation and improved outcome," explained senior author Steven Joffe, MD, MPH.

Although they didn't detect an immediate benefit for study participants, Peppercorn and Joffe reaffirmed the importance of trial participation, and they suggested that their findings should shift the emphasis on recruitment of trial patients. "We strongly encourage cancer patients to consider enrolling in clinical trials because their involvement can help improve cancer treatments over time," stated Peppercorn. "Many patients find it rewarding to know that they are contributing to the larger fight against cancer."


DOLについて - 利用規約 -  会員規約 -  著作権 - サイトポリシー - 免責条項 - お問い合わせ
Copyright 2000-2025 by HESCO International, Ltd.