New guidelines suggest that most patients with heart disease do not need antibiotic prophylaxis for infective endocarditis before undergoing dental procedures

Most patients with heart disease do not need antibiotic prophylaxis for infective endocarditis before undergoing dental procedures, according to new guidelines from the American Heart Association published online April 19 by Circulation.

The revised guidelines on prevention of infective endocarditis were based on a review of new and existing scientific evidence. In the revision, antibiotics prior to dental work are now only recommended for patients at greatest risk of negative outcomes from infective endocarditis: This includes patients with artificial valves or certain congenital heart conditions, heart transplant recipients who develop cardiac valve problems, recipients of an artificial patch to repair a congenital heart defect within the past six months, and patients with a history of infective endocarditis.

The new guidelines are based on a growing body of scientific evidence that shows the risks of taking preventive antibiotics outweigh the benefits for most patients. The risks include adverse reactions that range from mild to potentially severe and, in rare cases, are life-threatening or lethal. Inappropriate use of antibiotics can also lead to development of drug-resistant bacteria.

The guidelines state that patients who took prophylactic antibiotics routinely in the past but no longer need them include people with mitral valve prolapse, rheumatic heart disease, bicuspid valve disease, calcified aortic stenosis, or congenital heart conditions such as ventricular septal defect, atrial septal defect, and hypertrophic cardiomyopathy.


DOLについて - 利用規約 -  会員規約 -  著作権 - サイトポリシー - 免責条項 - お問い合わせ
Copyright 2000-2025 by HESCO International, Ltd.