PTSDは心停止後のリスクを上昇させる(American Heart Association's Resuscitation Science Symposium 2018, Abstract 13)

心的外傷後ストレス障害は心停止後1年の合併症や死亡増加と関連がある
Post-traumatic stress disorder linked to increased complications and death a year after cardiac arrest
心的外傷後ストレス障害(PTSD)症状は心停止経験者の主要心血管イベントおよび死亡のリスクを、初回医学的危機後最長1年間有意に上昇させる可能性があるとの予備的研究結果が、American Heart Association's Resuscitation Science Symposium 2018 で発表された。軽度から中等度の脳傷害を負った連続114人の患者のうち、31.6% が退院時(心停止後平均21日後)に心停止によるPTSDと診断された。1年以上の追跡期間中に、8.8% が死亡し、25.4% が心筋梗塞、重症狭心症、心不全または緊急血行再建術施行、あるいは除細動/ペースメーカー植込みによる入院などの重大な心血管有害イベントを再発した。
Full Text

Post-traumatic stress disorder (PTSD) symptoms may significantly increase cardiac arrest survivors' risk of major cardiovascular events and death up to a year after the initial medical crisis, according to preliminary research presented at the American Heart Association's Resuscitation Science Symposium 2018 – an international conference highlighting the best in cardiovascular resuscitation research.  The Resuscitation Science Symposium is part of the American Heart Association's Scientific Sessions 2018.

PTSD, which is common following cardiac arrest, was associated with a three-fold increased risk of death from any cause or a major heart event in a review of 114 patients who had been resuscitated after in-hospital or out-of-hospital cardiac arrest between 2015 and 2017.

Of 114 consecutive patients who survived with mild to moderate brain injury, 36 (31.6 percent) were diagnosed with cardiac-arrest-induced PTSD at discharge, which was an average of 21 days after the cardiac arrest. During the follow up of more than a year, 10 patients (8.8 percent) died and 29 (25.4 percent) experienced a recurrent major adverse cardiovascular event, such as rehospitalization due to myocardial infarction, severe angina, heart failure or an emergency revascularization procedure or defibrillator/pacemaker implantation.

The primary author is Sachin Agarwal, M.D., MPH of Columbia University Medical Center, New York, NY.

Researchers recommend further study to understand the underlying mechanisms.